This is Biohacking Weekly — a curated news roundup designed to help you increase your longevity, improve healthspan and access OptimOZ product picks.
1. The nutrigenomics effect
2. Dr. Peter Attia on your body’s “engine size”
3. The microbiome shortcut to ending constipation
4. How bright nights turn into heart trouble
5. Gluten sensitivity isn't about gluten
Imagine tweaking your meals to supercharge your body's built-in cleanup system? Researchers at the University of Palermo unpack how autophagy (your cells' recycling process that clears damaged parts) teams up with nutrigenomics, the science of how food tweaks gene expression.
This combo fights chronic issues like diabetes, brain decline, and cancer by curbing inflammation and boosting cell health. Foods rich in spermidine (from wheat germ and soy), omega-3s, and plant polyphenols can all help spark this cleanup system.
Source: Chiarelli R. et al., Frontiers in Nutrition (2024)
Oxford Healthspan Primeadine is a natural spermidine supplement that supports your body’s “cell self-cleaning” process — autophagy.
Spermidine is found in foods like wheat germ and soy, but levels in the body decline with age. Primeadine® helps restore them, promoting smoother cell renewal, better focus, and stronger hair and skin.
It’s also available in a gluten-free formula, perfect for sensitive systems.
On the latest episode of 60 Minutes, longevity expert Dr. Peter Attia urged viewers not to overlook cardio. While strength training dominates modern fitness culture, he said VO₂ max — the measure of how efficiently the body uses oxygen during exercise — is one of the strongest predictors of how long and how well we live.
Dr. Attia calls VO₂ max “the size of your engine” and emphasises training the heart and lungs as much as muscles. He believes cardiorespiratory fitness and strength together predict longevity better than cholesterol or blood pressure ever could.
A new study has revealed that psyllium husk powder doesn’t just ease constipation — it transforms the gut from the inside out. Researchers found that this natural fiber supplement improved defecation time, stool hydration, and intestinal motility in mice with constipation. It also increased short-chain fatty acids (SCFAs), compounds known to nourish gut cells and reduce inflammation.
Beyond simple relief, psyllium reshaped the gut microbiota, boosting beneficial bacteria like Akkermansia muciniphila while cutting down harmful ones. Scientists concluded that psyllium’s power lies in restoring microbial balance and activating metabolic pathways that keep the gut healthy and the bowels moving.
Source: Wang Z. et al., Food Bioscience (2025)
A massive study analyzing 13 million hours of light exposure has found that bright light at night can raise the risk of heart failure by 56% and heart attack by 47%. Researchers from Flinders University tracked nearly 89,000 people over 9.5 years and discovered that even moderate nighttime lighting, like a bedside lamp, can disrupt the body’s circadian rhythm and strain the heart, especially in younger adults and women.
On the flip side, bright daylight exposure offered protection, lowering the risk of coronary artery disease by 13%, heart failure by 28%, and stroke by 27%. Scientists say this highlights a simple biohacking rule: keep nights dark and days bright.
Source: Windred D. et al., JAMA Network Open (2025)
If gluten-free living hasn't fixed your bloating, gut cramps, or tiredness, here's why: a recent Lancet review suggests that many cases of non-coeliac gluten sensitivity (NCGS) are actually driven by fermentable carbs — specifically FODMAPs in wheat. These are simple sugars that gut bacteria feed on, producing gas and discomfort.
There’s another layer too: the nocebo effect. When your brain expects a food to cause trouble based on past experiences, it can trigger real symptoms — even when the food itself is harmless. In blinded tests, people reacted just as strongly to placebos as to gluten.
👉 Read the full article on The University of Melbourne website
In this edition of Biohacking Weekly:
1. Why your vitamin D might still be low
2. Heart-health gap between men and women
3. How music may guard against dementia
4. 10+ reasons not to toss your pumpkin seeds this Halloween
5. The little-known “spring asthenia”
In this edition of Biohacking Weekly:
1. Protein quality over quantity
2. Can food mimic ozempic?
3. The silent sleep stealer
4. Keto may guard against Alzheimer’s
5. Diet that brings psoriasis relief
In this edition of Biohacking Weekly:
1. The role of magnesium in cancer prevention
2. The heartbeat economy of exercise
3. Data that redefines ‘full-time’ work
4. Why your brain peaks at 55
5. UV light turns off allergy triggers
