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BIOptimizers Cognibiotics - 60 capsules

CogniBiotics¬ģ is the most powerful mood and mind-enhancing probiotic available.¬†

Cognibiotics combine the power of Chinese medicine with synergistic brain-boosting probiotics.

10 probiotic strains delivering 30 billion CFU
17 Chinese Herbs Blend
Prebiotic Inulin and Xylooligosaccharides


  • A nootropic blend that improves brain health, mental clarity, learning, memory, and focus by improving the gut bacteria
  • Helps with brain fog and procrastination
  • Promotes relaxation and balanced stress responses
  • Contains 17 nootropic and adaptogenic herbs that boost cognitive function, mood, and stress resilience by improving your gut flora
  • A powerful synergy of 10 brain-friendly probiotic bacteria strains, which have been shown to boost mood and cognitive function
  • Improves the balance of neurotransmitters in the brain
  • Improves neuroregeneration and neuroplasticity by improving BDNF and NGF, which boost learning capacity and mood
  • Protects the brain against oxidative stress
  • Improves blood flow to the brain
  • Supports digestive health and regularity

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  • Most nootropics and adaptogens only target the brain, which leaves out the key pieces of your cognitive function and mental health: your gut and the gut microbiome. Cognibiotics is the only probiotic-nootropic blend on the market that improves the entire gut-brain-microbiota axis.

    The formula contains a powerful combination of 17 herbs known to boost mood and cognitive function by improving the gut microbiome. In addition, the 10 bacteria strains in Cognibiotics work synergistically to boost brain health and promote a balanced stress response.

    • Formulated by expert Chinese Herbal Scientists
    • The 2,200-year-old Chaihu Shugan San herb blend improves mood, brain health, and happiness through the gut microbiome
    • 10 research-based bacteria strains that synergize to improve mood and cognitive function
    • Prebiotic complex boosts probiotic survival and effectiveness
    • Adaptogenic: calming, promotes a balanced-stress response and mitigates negative health effects of stress
    • Nootropic: boost memory and learning, and maintain healthy brain function amidst stress
    • Improves mood and happiness
    • Protects the brain with antioxidants that can enter the brain
    • Supports neuroplasticity, which improves brain adaptation and healing
    • Can be taken on an empty stomach or with meals
    • 100% Satisfaction guarantee with respect to quality, purity, potency, and effectiveness
    • Produced in small batches with medical-grade ingredients.

    Cognibiotics Benefits

    1. Improves Brain Health Through the Gut-Brain-Microbiome Axis

      Your gut feeling is an example of how your gut works with your brain. Recent research shows that gut health and the gut microbiome strongly influence brain health. Your gut bacteria can control your thoughts, emotions, and stress resilience. Also, many people with mental health and neurological disorders have dysbiosis and digestive issues. Often, an improvement in gut bacteria composition.

      Cognibiotics contain bacteria strains that are known to improve mood and cognitive function. In addition, the Chaihu Shugan San herb formula in Cognibiotics works by improving the have dysbiosis and digestive issues. However, Cognibiotics is only meant for general brain health and not approved to treat any disease.

      • Boost BDNF (Brain-Derived Neurotrophic Factor)
      • Boost low mood, reduce anxiety
      • Reduce stress
      • Produce mood-boosting vitamins (e.g. K and B-12)
      • Rejuvenate your brain and improve brain-gut connection
      • Generate happiness chemicals
      • Enhance cognitive performance
    2. Promote a Balanced Stress Response and Stress Resilience

      Stress can cause anxiety, poor sleep, abnormal appetite, reduced performance, and many other negative health effects. Adaptogens are herbs or substances that help reduce the stress response, promote calmness, or improve your ability to deal with the stress. Cognibiotics contain several adaptogenic herbs such as Schisandra and Chinese licorice.

    3. Promote Healthy Acetylcholine Levels

      Acetylcholine is an important neurotransmitter for learning and memory. P. multiflorum, S. miltiorrhiza, and R. glutinosa in Cognibiotics are cholinergic herbs that increase acetylchol levels.

    4. Improve Neurotransmitter Balance

      In animal studies, the probiotics L. plantarum, L. helveticus, L. fermentum, L. rhamnosus, and B. infantis promote the balance of neurotransmitters in the brain. The good bacteria also help ensure that the used neurotransmitters are

    5. Improve Brain-Derived Neurotrophic Factor

      The good bacteria and herbs in Cognibiotics work together to stimulate the production of proteins that help the brain grow, reorganize, and adapt. These proteins include brain-derived neurotrophic factor (BDNF) and neural growth factor (NGF). Increasing these proteins help with learning, memory, and mood.

    6. Protecting Neurons Against Oxidative Stress

      Oxidative stress comes from mental-emotional stress, toxic exposure, inflammation, poor diet, unhealthy lifestyle, and more. Nowadays, most people don’t consume enough antioxidants in their diets. When oxidative stress exceeds your body’s antioxidant capacity, it can damage cells. Oxidative stress can contribute to brain fog, fatigue, and neurologic disorders.

      Herbs in Cognibiotics contain antioxidants that can cross the blood-brain barrier and protect your brain from day-to-day oxidative stress.

    7. Increases Blood Flow to the Brain

      Your brain needs oxygen and vital nutrients to work well, but it’s also the organ that’s hardest to deliver blood to. It’s located at the highest point in the body and has many tiny blood vessels. Stress, poor blood vessel health, oxidative stress, and low blood pressure can reduce blood flow to the brain. When the brain gets reduced blood flow, it doesn’t get healthy levels of oxygen and nutrients. The deprivation can cause fatigue, brain fog, poor cognitive function, and low mood.

      The Chaihu-Shugan San herb formula normalizes brain blood flow in depression patients.

    8. Producing Beneficial Postbiotics, Such as Butyrate

      Postbiotics are produced when your probiotic bacteria ferment the prebiotic fibers, such as the small fatty acids propionate and butyrate.

      Low mood, brain fog, and fatigue are caused by sluggish neurons that can’t produce enough energy (ATP). The small fatty acids. can enter the brain, energize the sluggish neurons, and lower oxidative stress Your neurons can also burn the fatty acids for energy. Butyrate also boosts BDNF levels.

      The small fatty acids also counteract chronic inflammation and strengthen the gut and blood-brain barriers. They also promote a healthy metabolism and blood sugar levels, which are important for brain health.

    How CogniBiotics Works?

    Cognibiotics combine the power of Chinese medicine with synergistic brain-boosting probiotics.

    Cognibiotics contains two Traditional Chinese Medicine formulas traditionally used for both mental health and digestive issues by promoting harmony between the brain and the gut

    • The Chai Hu Shu Gan San formula, which improves stress resilience, mood, and cognitive function by improving the gut flora
    • The An Shen Bu Xin San formula, traditionally used to calm the spirit, contains several cognitive performance-enhancing herbs


    These herb formulas were invented 2,200 years ago, but modern-day research has shown that they boost neurotransmitter levels, improve the gut microbiome, and combat oxidative stress. They are also adaptogenic herbs that promote a balanced stress response.

    The beneficial bacteria boost mood, wellbeing, memory while promoting a balanced stress response by:

    • Directly speaking to your brain via the vagus nerve that links between the gut and the brain
    • Controlling your happy, rewarding and relaxing neurotransmitter
    • Producing beneficial nutrients that can jump-start sluggish neurons and combating oxidative stress
    • Boosting neuronal growth and branching, such as by increasing a protein called BDNF, which improves happiness and memory
    • Promoting a healthy and balanced stress response
    • Promoting a balanced inflammatory response, since excess inflammation can contribute to mental health and cognitive problems


    When To Take CogniBiotics?

    The goal is to deliver the probiotics to your large intestine relatively intact and maximize absorption of the herbs, so you want to minimize their exposure to your stomach acid and digestive enzymes. Your gut secretes digestive enzymes and stomach acid when you have food in your stomach. Therefore, you should take your Cognibiotics on an empty stomach. However, if you get stomach upset from taking it without food or cannot take it without food for any other reasons, it is still beneficial when taken with meals.

    Take Cognibiotics first thing in the morning on an empty stomach. Some people also find significant cognitive and mood boosts when they take Cognibiotics before or with lunch and dinner.

    Because Cognibiotics contain probiotics, be sure to take it at least an hour away from antibiotics or supplements that have antibacterial properties.

    Cognibiotics and Depression

    The latest research shows that, aside from life events, the following factors contribute to depression, cognitive dysfunction, and other mental health problems:

    Cognibiotics promotes good mood, mental health, cognitive function, and stress resilience by:

    • Improving the gut microbiome
    • Energising the neurons
    • Promoting a balanced immune response
    • Supporting the gut and brain barriers
    • Promoting digestive health
    • Supporting blood sugar control

    • Directions:

      The recommended dose for CogniBiotics¬ģ can be found on the label - 2 capsules a day on an empty stomach upon waking. 30 Servings per bottle.

      However, in clinical experience, we have found the effective dose for most people is 2 capsules in the morning, 2 capsules with breakfast, and 2 capsules in the evening.

      If you want to start slow, take 2 capsules with breakfast and 2 capsules with dinner.

      10 probiotic strains delivering 30 billion CFU per serving, together with Prebiotic Inulin and Xylooligosaccharides and the Chinese Herbal Blend. Other ingredients: L-leucine, silica, hypromellose (capsule)

      Caution: Keep out of reach of children. As with any product, discontinue immediately if advert effects occur. Please consult a physician before beginning any new supplement, diet, training program, or if you’re undergoing treatment of a medical condition.

      [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2077351/
      [2] https://www.frontiersin.org/articles/10.3389/fnagi.2016.00256/full
      [3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102282/
      [4] https://www.cpn.or.kr/journal/view.html?doi=10.9758/cpn.2015.13.3.239
      [5] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314114/
      [6] https://journals.lww.com/ajg/Fulltext/2019/07000/Bifidobacterium_longum_1714__Strain_Modulates.25.aspx
      [7] https://www.mayoclinic.org/diseases-conditions/depression/expert-answers/vitamin-b12-and-depression/faq-20058077
      [8] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102282/
      [9] https://www.ncbi.nlm.nih.gov/pubmed/26408987
      [10] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707719/
      [11] https://www.ncbi.nlm.nih.gov/pubmed/26896291
      [12] https://www.sciencedirect.com/topics/medicine-and-dentistry/bifidobacterium-animalis
      [13] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265827/
      [14] https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219633
      [15] https://www.health.harvard.edu/flu-resource-center/how-to-boost-your-immune-system.htm
      [16] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707719/
      [17] https://www.ncbi.nlm.nih.gov/pubmed/26896291
      [18] https://www.sciencedirect.com/topics/medicine-and-dentistry/bifidobacterium-animalis
      [19] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265827/
      [20] https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219633
      [21] https://www.health.harvard.edu/flu-resource-center/how-to-boost-your-immune-system.html
      [22] https://www.ncbi.nlm.nih.gov/pubmed/22097208
      [23] https://www.sciencedirect.com/science/article/abs/pii/S075333221830369X

    Customer Reviews

    Based on 14 reviews
    Neville Webb (Melbourne, AU)

    The best

    Tim (Brisbane, AU)

    Cognibiotics, p3om, magnesium, coffee, zinc, it‚Äôs all superb.. Helps the brain & stomach.. Lots less gas these days ūüėČ, sleeping better, more energy ūüėÉūüėÉ.. The follow up answering of my questions is excellent also.

    Denisa Zubajova (Sydney, AU)
    Mood improvement

    Absolutely in love with this product, mental clarity, less brain fogs and moods improvement - especially during the PMS. Started feeling the difference after first month of using.

    Grateful weaver (Brisbane, AU)
    Keeps me moving

    Top to bottom this is the right gear. Gut, brain and bottom are all running smoothly.

    Pranita Sharma (Port Moresby, PG)
    Focus and better mindset

    These tablets have allowed me to remain focused at work for long hours without having to supplement my day with too much caffeine!