This is Biohacking Weekly - A curated news roundup designed to help you increase your longevity, improve healthspan and access OptimOZ product picks.
1. Inflammaging - the silent age accelerator
2. Can lifestyle choices fight Parkinson’s?
3. How copper may help delay age-related cognitive decline
4. Is fibermaxxing worth the hype?
5. Superfood from Australia’s stingless bees
After age 50, gut bacteria diversity declines. Helpful microbes like Bifidobacterium decrease, while potentially harmful ones like E. coli increase. This shift is linked to weaker immunity, frailty, and faster aging. Interestingly, long-lived individuals tend to have a more stable and diverse microbiome, rich in species like Akkermansia and Lactobacillus, which are associated with better health in old age.
These microbial changes can trigger “inflammaging” — chronic, low-grade inflammation that speeds up aging in the brain, muscles, bones, and immune system. A weakened gut lining lets inflammatory molecules enter the bloodstream. As immune surveillance declines, a vicious cycle begins: a leaking gut fuels inflammation, the immune system becomes impaired, and ageing accelerates.
Read the full article on BBC Science Focus
As we age, our gut microbiome naturally shifts — often losing beneficial bacteria that help protect against inflammation and disease. Layer Origin’s formulas use Human Milk Oligosaccharides (HMOs) — a type of prebiotics originally found in breast milk, but now produced through precise fermentation (with no actual breast milk involved).
Research shows HMOs help strengthen the gut barrier, reduce chronic inflammation, and support a healthier immune response, making them a powerful tool for maintaining gut health and resilience.
Explore Layer Origin Supplements
Legendary rock star Ozzy Osbourne has died at 76 after a long battle with Parkinson’s disease. The brain disorder, which causes tremors, stiffness, and movement issues, slowly worsened over the years despite treatment. Osbourne spoke openly about his condition, raising awareness of the struggles faced by others living with this progressive illness.
Although there is still no cure, research suggests that lifestyle choices may help lower the risk or slow the progression of Parkinson’s. A large UK Biobank study found that people who exercised for at least 150 minutes a week had a significantly reduced risk of developing the disease. [Source]
Nutrition may also play a role. A 2025 review highlighted four natural compounds —Coenzyme Q10, resveratrol (found in grapes), lycopene (from tomatoes), and omega‑3 fatty acids — that may help protect brain cells by reducing inflammation and cellular stress. These findings support the idea that diet and supplements could be part of a broader strategy for brain health. [Source]
Read the full article on The Independent
A new study analyzing data from over 2,400 older adults in the U.S. has found that moderate copper intake — about 1.2 to 1.6 milligrams per day — is linked to better brain function. Participants in this intake range performed better on tests measuring memory, focus, and processing speed. However, going above or below this range did not show the same benefits, suggesting that the right balance of copper may support brain health during aging.
Copper is essential for several key brain functions. It helps generate energy in cells, supports communication between brain cells, and protects brain tissue from damage. It also plays a role in managing oxidative stress and inflammation, which are linked to age-related cognitive decline. Too little copper can weaken brain signaling, while too much may contribute to harmful inflammation.
Read the full article on Medical News Today
A wellness wave called fibermaxxing is sweeping across TikTok — and this one might be worth the hype. The trend encourages people to deliberately increase their fiber intake, and dietitians are praising it for more than just digestive benefits. According to experts, fiber helps regulate blood sugar, lowers cholesterol, supports healthy weight, and even plays a role in reducing the risk of chronic diseases like type 2 diabetes, cardiovascular disease, and premature death. Plus, fiber-rich foods like leafy greens and nuts can even support liver detoxification and promote satiety, leading to better calorie control and overall wellness.
Fiber also feeds gut bacteria that produce short-chain fatty acids like butyrate, which nourish colon cells and fight inflammation. Excitingly, new research even shows that people with colon cancer may live longer if they increase fiber intake.
But don’t go from zero to 40 grams of fiber overnight — experts warn that rapid increases can cause bloating and discomfort. Instead, start gradually: add berries to breakfast or swap in high-fiber meals over a couple of weeks.
Read the full article on CNN Health
New research from the University of Sydney has revealed that sugarbag honey — from Australia’s native stingless bees — has powerful and consistent antimicrobial properties. It effectively kills bacteria and fungi even after heating and long-term storage. Unlike regular honey, it works by slowly releasing hydrogen peroxide over days and also has non-peroxide antimicrobial effects. The potency remains stable across different environments, suggesting the bees, not just the flowers, are behind its unique power.
Used traditionally by Indigenous Australians for skin healing, sugarbag honey now shows promise as a natural defense against drug-resistant microbes. Each hive produces only 0.5 liters a year, but the honey’s remarkable strength and unique antimicrobial properties make it a promising biohacking tool for boosting healthspan.
Read the full article on New Atlas
🦠 Gut Shift After 50
Microbiome diversity drops after 50,with harmful bacteria rising and beneficial ones like Bifidobacterium declining — driving inflammation, frailty, and accelerated aging.
🧠 Ozzy Osbourne and Parkinson’s Awareness
Ozzy’s death at 76 spotlights Parkinson’s — exercise and compounds like CoQ10 and Omega-3s may slow its progression, though no cure exists.
🧪 Copper Sweet Spot for Brain Health
in older adults, but too little or too much may harm brain function.
🌾 Fibermaxxing Has Real Benefits
Upping fiber intake aids gut health, lowers disease risk, and supports weight control — but increase it slowly to avoid digestive distress.
🍯 Sugarbag Honey: Nature’s Antimicrobial Powerhouse
Australian stingless bee honey kills bacteria and fungi even after heating, making it a potent natural remedy with biohacking promise.
🔥 Product Top Picks
🔍 Dive Deeper Into Related Topics
In this edition of Biohacking Weekly:
1. Red flag ingredients hiding in your coffee creamer
2. What happens when you walk backwards?
3. Why insulin resistance goes unnoticed
4. Fat burn on keto: men vs. women
5. UK’s mega scan project uncovers hidden health clues
In this edition of Biohacking Weekly:
1. Why frequent nightmares could be a red flag for longevity
2. How mindset can turn back the clock
3. New study links diet to generational loss of gut diversity
4. What a little sun can really do (beyond vitamin D)
5. How to build muscle and lose fat at the same time
In this edition of Biohacking Weekly:
1. Super Agers unveils the science behind living longer
2. The alkalizing power of a plant-based diet
3. Social bonds shown to improve longevity
4. Cardioprotective effects of green vegetables
5. Multivitamins delay aging and cognitive decline
