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PureHMO® Human Milk Oligosaccharide Super Prebiotic Powder

Bio-identical Human Milk Oligosaccharides. 2'-Fucosyllactose (2'FL) PREBIOTIC FIBRE INSPIRED BY MOTHER'S MILK

Human milk oligosaccharides (HMOs) are a super prebiotic occurring naturally in mother's milk. Today, through precise fermentation from dairy lactose, bio-identical HMO delivers all the benefits without any actual human milk in the product. PureHMO® Prebiotic Powder contains 45 one-scoop servings of 1950mg each.  Also available in capsules.

  • Promote Healthy Gut Microflora: HMO prebiotic powder promotes the growth of probiotics like Bifidobacterium and Akkermansia Muciniphila.
  • Improve Immune System: HMO are more effective than traditional prebiotics (GOS, XOS, Inulin) in stimulating innate immune system, inhibiting pathogens & reducing inflammation. 
  • Support Cognitive Health: Unlike other probiotic prebiotic for adults, HMO metabolites promotes brain development, neuronal transmission, and cognition.
  • 45 x 1950mg servings of powder.

      Scientists have identified over 200 different complex sugar molecules, known as human milk oligosaccharides (HMOs), in humans. In other mammals there are only about 50. After lactose and fats, these sugars are the third most abundant component in human milk. But humans are missing the enzymes needed to process those sugars so they pass through the stomach and into the small intestine, undigested.

      The sugars nourish a very important subspecies of bacteria called Bifidobacterium longum infantis, which then raises the acidity of the substrate as it feeds off of the HMOs.

      Inside the gut, this makes the environment more hostile to pathogens like E.Coli. The bacteria B. infantis also boosts production of proteins that close gaps between gut cells to keep microbes out of the bloodstream and increases anti-inflammatory molecules that boost the immune system. To achieve those beneficial results, B. infantis has to feed on HMOs. 


      2'-Fucosyllactose is one type of Human Milk Oligosaccharide. There are more than 200 different types of HMOs in all with 2'-FL as the most abundant variety accounting for about 30% of all HMOs. It is an oligosaccharide - specifically it is fucosylated, neutral trisaccharide composed of L-fucose, D-galactose, and D-glucose units. It can be biosynthesized at scale using E. Coli. 

      As with other oligosaccharides, a main characteristic of 2'-Fucosyllactose is its ability to protect against infectious disease. It's best known for preventing epithelial level adhesions of toxins and pathogens. The 2'-FL stimulates the growth of bifidobacteria and receptor analogons which leads to toxic and pathogenic protection. 2'-FL is known to protect against Campylobacter jejuni, Salmonella enterica serotype Typhimurium, Helicobacter pylori, and others.

      Research into the various health benefits of HMOs has accelerated as more HMO varieties become commercially available at scale. We're ranking benefits based on data and findings in research publications on HMOs. There is extensive researching demonstrating that 2'FL and LNnT provide benefits for gut health. There is some evidence, but not quite as strong, that both 2'FL and LNnT provide benefits for immune health. Brain health is boosted by 2'FL, 3'SL, and 6'SL according to some of the available research.

      Be sure to choose the right human milk oligosaccharide supplement for you, whether it is a 2'-FL supplement, or one that is a combination — a 2'-Fucosyllactose, Lacto-N-neotetraose supplement. 


      Both human milk oligosaccharides (HMOs) and prebiotic oligosaccharides (PBOs) belong to the large class of carbohydrates, but they have com­pletely different structures.

      Human Milk Oligosaccharides have been growing in popularity in human nutrition since 2015. HMO is naturally found in breast milk and serves as nature's preferred prebiotic. They are produced in the lactating mammary glands

      HMO is a special prebiotic that's quite different from GOS, FOS, and XOS because of where it comes from.

      Human Milk Oligosaccharide (HMO) consists of complex sugar molecules. Unlike GOS, FOS, and even XOS, which can cause some of same problems people take them to avoid (gas, bloating, IBS sypmtoms), HMO does not have that effect.

      When considering the difference be¬tween GOS/FOS and HMOs, two major aspects have to be considered:

      (A) The monosaccharide composition

      (B) The linkage between them. The linkage is very important because specific functions including defense mechanisms, immune functions, or anti-inflammatory effects strongly de-pend on those linkages.


      Research has shown that 2'-FL supports the development of a healthy gut and immune system, protection against allergic diseases and plays a role in the development of normal brain functions and cognition in early life and beyond.

      2'FL has been shown to be vital for digestive health by promoting growth of beneficial bacteria, inhibit adhesion of pathogens, quenching inflammation and normalizing gut movements.

      *HMOs primarily increase a type of intestinal microbiota called Bifidobacteria. 

      In a study of health adults charting Bifidobacteria fold change over the baseline amount, HMOs were shown to beneficially modulate the intrinsic intestinal microbiota. 

      The two HMOs tested were 2'FL and LNnT. They were compared to a placebo. 


    Customer Reviews

    Based on 11 reviews
    Brenda Rowlandson (Sydney, AU)
    HMO Good Results

    After having my microbiome done, my naturopath recommended HMO as my bifidobactera measured almost zero. It is recommended that you start small and build up to 2 scoops a day over time. In combo with pancreatic enzymes and a high powered short term probiotic, my gut symptoms eased and I now feel lighter & brighter, my brain works better, bloating & gas are a thing of the past. You need to give it a few months as a dysbiotic gut takes time to adapt and heal. It dissolves easily in a drink and tastes mildly pleasant if sprinkled on food. Excellent product. I am happy to recommend it.

    Karri Ward (Perth, AU)
    Game changer

    Since introducing HMO’s in to my daily routine I have never looked back. These were a huge part of healing my digestive issues and continue to be a staple addition to my morning regimen. Thank you Optimoz for making these available to us 🙏

    lynn (Sydney, AU)
    Great product

    Easy to add to my morning coffee - dissolves easily in cold or hot liquid.

    Lion (Sydney, AU)
    Perfect Amino

    Great taste and easily digestible.

    Sukhbir Dhillon (Melbourne, AU)
    PureHMO® Human Milk Oligosaccharide Super Prebiotic Powder

    It’s a great start to the day. I have a scoop with my bulletproof coffee. It kick starts my motions and keeps me going for the rest of the day.