

Layer Origin 6'-SL Prebiotic Powder Australia | 60 Serves
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Prebiotic Powder · 6′-Sialyllactose (6′-SL) · FORMULATED SUPPLEMENTARY SPORTS FOOD 60 Servings
Layer Origin 6′-Sialyllactose Prebiotic Powder
A single-ingredient prebiotic powder containing 6′-Sialyllactose (6′-SL), an acidic/sialylated human milk oligosaccharide produced through precision fermentation. Bio-identical to the 6′-SL naturally found in human milk.
60 servings · No flavour, no sweetener, no fillers.
What This Product Is
Human milk oligosaccharides (HMOs) are complex carbohydrates that occur naturally in human breast milk. Researchers have identified over 200 different HMO structures, which fall into two broad categories: neutral HMOs (such as 2′-FL, LNT, LNnT) and acidic / sialylated HMOs (such as 3′-SL and 6′-SL).
6′-Sialyllactose (6′-SL) is one of the sialylated HMOs. It is a trisaccharide composed of sialic acid linked to lactose, with the sialic acid attached at the 6′ position of the galactose unit. This positional linkage distinguishes 6′-SL from 3′-SL (where sialic acid is at the 3′ position).
This product contains 6′-SL as the single active ingredient, manufactured through precision fermentation. The 6′-SL produced this way is chemically identical (bio-identical) to 6′-SL naturally present in human milk, while containing no actual human milk in the product.
Regulatory status: 6′-SL is one of six HMOs approved by Food Standards Australia New Zealand (FSANZ) for use as a food ingredient in Australia and New Zealand.
What’s in Each Serve
| Ingredient | Amount |
|---|---|
| 6′-Sialyllactose (6′-SL) | Refer to Supplement Facts panel |
Single-ingredient formulation. No flavouring, no sweeteners, no fillers, no preservatives.
How HMO Prebiotics Work
A prebiotic is a food substance that the human body does not digest itself. HMOs pass through the stomach and small intestine unchanged and reach the colon, where they become available as food for certain bacterial species in the gut. Different bacteria preferentially consume different prebiotic substrates.
HMOs are not digested by human enzymes — humans lack the specific enzymes needed to break them down. They are consumed by particular bacterial species that do have these enzymes.
Neutral HMOs vs Sialylated HMOs
Human milk HMOs are broadly classified into two structural categories:
| Category | Examples | Characteristic |
|---|---|---|
| Neutral HMOs | 2′-FL, LNT, LNnT | No sialic acid; majority of total HMO content in human milk |
| Sialylated (Acidic) HMOs | 6′-SL, 3′-SL | Contain sialic acid; smaller acidic fraction of human milk HMOs |
6′-SL is one of the sialylated HMOs. Sialylated HMOs are structurally distinct from neutral HMOs because they contain sialic acid (N-acetylneuraminic acid), which gives them their acidic character.
Product Specifications
| Format | Powder (single ingredient, mix into beverage) |
| Servings per Container | 60 |
| Net Weight | 180g |
| Active Ingredient | 6′-Sialyllactose (6′-SL) — refer to Supplement Facts panel for per-serving amount |
| Other Ingredients | None (single-ingredient powder) |
| Source | Precision fermentation. Bio-identical to natural human milk 6′-SL. |
| Dietary Suitability | Contains derivative of dairy lactose. Not suitable for severe dairy allergy. |
| Storage | Store in a cool, dry place. Keep tightly closed after opening. |
Directions for Use
Starting dose: Take half a teaspoon per day for the first few days to assess individual tolerance.
Maintenance: Increase to one teaspoon per day as tolerated.
How to mix: Dissolves into water, juice, smoothies, or other beverages. The powder is essentially flavourless.
Refer to the product label for full guidance. Do not exceed the recommended daily intake.
The Layer Origin HMO Range
Layer Origin offers three HMO prebiotic products at OptimOZ, each suited to different preferences:
- PureHMO® Prebiotic Powder — single ingredient, 2′-FL only (a neutral HMO). 45 servings, 1,950mg per scoop. Lowest price point. The most abundant single HMO in human milk.
- 6′-SL Prebiotic Powder (this product) — single ingredient, 6′-SL only (a sialylated HMO). 60 servings, 180g. Premium price point. The sialylated HMO option for users wanting an acidic-fraction HMO.
- SuperHMO® Prebiotic Mix — five-HMO blend including both neutral (2′-FL, LNT, LNnT) and sialylated (3′-SL, 6′-SL) HMOs. Top price point. Widest range of HMO structures.
Good to Know
Does this product contain actual human milk?
No. The 6′-SL in this product is produced through fermentation. It is chemically identical to the 6′-SL naturally found in human milk, but no human milk is used in production. The "Human Milk Oligosaccharide" terminology refers to the chemical category of the ingredient, not the source.
How is 6′-SL different from 2′-FL?
Both are HMOs, but they belong to different structural categories. 2′-FL is a neutral HMO (containing fucose, no sialic acid). 6′-SL is a sialylated HMO (containing sialic acid, which gives it an acidic character). In human milk, neutral HMOs are present in higher quantities than sialylated HMOs by mass. Both categories have distinct structural properties.
How is 6′-SL different from 3′-SL?
Both are sialylated HMOs containing sialic acid, but they differ in the position where sialic acid is attached to the lactose backbone. 6′-SL has sialic acid at the 6′ position of the galactose unit; 3′-SL has it at the 3′ position. This positional difference gives them distinct structural properties.
Is this product suitable for infants or children?
No. This product is formulated as an adult dietary supplement. It is not intended for use in infants, toddlers, or children. While 6′-SL and several other HMOs are approved by FSANZ for use as food ingredients in Australia — including in infant formula products — the formulation, dose, and presentation of infant-formula HMOs are different and regulated separately. Do not give this product to infants or children.
Is this product vegan?
No — the 6′-SL is produced through fermentation from dairy lactose, so the source is dairy-derived. The fermentation process means the final product contains no intact dairy proteins or significant amounts of lactose, but it is not classified as vegan.
Can I take this alongside PureHMO or SuperHMO?
SuperHMO already contains 6′-SL as part of its five-HMO blend, so taking 6′-SL alongside SuperHMO would mean a higher 6′-SL dose without additional HMO diversity. Taking 6′-SL alongside PureHMO (which is 2′-FL-only) provides both a neutral and a sialylated HMO. Most users choose one product based on their preference rather than combining them.
Does this product interact with any medications?
6′-Sialyllactose is a naturally-occurring food component with no known significant medication interactions. However, if you take prescription medication, particularly for digestive conditions, or are immunocompromised, consult a healthcare practitioner before use.
Important Information — Formulated Supplementary Sports Food
Formulated Supplementary Sports Food: This product is not a sole source of nutrition and should be consumed in conjunction with a nutritious diet and appropriate physical training or exercise program. Not suitable for children under 15 years of age or pregnant women: should only be used under medical or dietetic supervision.
Not for infant use: This product is formulated for adults. Do not give to infants, toddlers, or children. Infant formula products containing approved HMOs are regulated separately under different FSANZ standards.
Always read the label and follow the directions for use. Do not exceed the recommended daily intake. Use only if the seal is intact. Keep out of reach of children.
Dairy allergy: The 6′-SL in this product is derived from dairy lactose through fermentation. People with severe dairy allergies should consult a healthcare practitioner before use.
Consult a qualified healthcare practitioner before use if you are immunocompromised, take prescription medication, have a digestive condition, or have any pre-existing medical condition.
This product is not intended to diagnose, treat, cure or prevent any disease.
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